Article
TRIP6 enhances lysophosphatidic acid-induced cell migration by interacting with the lysophosphatidic acid 2 receptor.
The Journal of biological chemistry - 12 Mar 2004
Xu Jun, Lai Yun-Ju, Lin Weei-Chin, Lin Fang-Tsyr
Abstract excerpt
Lysophosphatidic acid (LPA) induces actin rearrangement, focal adhesion assembly, and cell migration through the activation of small G protein Rho and its downstream effectors. These diverse cellular responses are mediated by its associated G protein-coupled receptors. However, the mechanisms and...
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