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Article

TRIP6 enhances lysophosphatidic acid-induced cell migration by interacting with the lysophosphatidic acid 2 receptor.

The Journal of biological chemistry - 12 Mar 2004

Xu Jun, Lai Yun-Ju, Lin Weei-Chin, Lin Fang-Tsyr

Abstract excerpt

Lysophosphatidic acid (LPA) induces actin rearrangement, focal adhesion assembly, and cell migration through the activation of small G protein Rho and its downstream effectors. These diverse cellular responses are mediated by its associated G protein-coupled receptors. However, the mechanisms and specificity by which these LPA receptors mediate LPA actions are still poorly understood. Here we show that LPA...

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Share to ATPases Associated with Diverse Cellular Activities
Share to Focal Adhesion Kinase 1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Focal Adhesion Protein-Tyrosine Kinases

Share to LIM Domain Proteins

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Source

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Identifiers

PMID: 14688263
DOI: 10.1074/jbc.M311891200
PMCID: PMC3904432

Genes

LPA
TRIP6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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