Article
Cell surface receptors in lysophospholipid signaling.
Seminars in cell & developmental biology - 1 Oct 2004
Anliker Brigitte, Chun Jerold
Abstract excerpt
The lysophospholipids, lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P), regulate various signaling pathways within cells by binding to multiple G protein-coupled receptors. Receptor-mediated LPA and S1P signaling induces diverse cellular responses including proliferation, adhesion, migration, morphogenesis, differentiation and survival. This review will focus on major components of lysophospholipid...
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