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Article

HDL does not influence the polarization of human monocytes toward an alternative phenotype.

International journal of cardiology - 1 Mar 2014

Colin Sophie, Fanchon Mélanie, Belloy Loic, Bochem Andrea E, Copin Corinne, Derudas Bruno, Stroes Erik S G, Hovingh G Kees, Kuivenhoven Jan A, Dallinga-Thie Geesje M, Staels Bart, Chinetti-Gbaguidi Giulia

Abstract excerpt

BACKGROUND: Macrophages are crucial cells in the pathogenesis of atherosclerosis. Macrophages are plastic cells which can switch from a classical pro-inflammatory M1 to an alternative anti-inflammatory M2 macrophage phenotype, depending on the environmental stimuli. Because high-density lipoprotein (HDL) cholesterol levels are inversely correlated to cardiovascular disease and since HDL displays anti-inflammatory...

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PMID: 24456889
DOI: 10.1016/j.ijcard.2013.12.168

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ABCA1
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PTX3

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