Article
Differentiation of circulating monocytes into macrophages with metabolically activated phenotype regulates inflammation in dyslipidemia patients.
Clinical and experimental immunology - 13 May 2022
Berenice Martínez-Shio Elena, Martín Cárdenas-Hernández Ángel, Jiménez-Suárez Verónica, Sherell Marín-Jáuregui Laura, Castillo-Martin Del Campo Claudia, González-Amaro Roberto, Escobedo-Uribe Carlos D, Monsiváis-Urenda Adriana Elizabeth
Abstract excerpt
Macrophages are mediators of inflammation having an important role in the pathogenesis of cardiovascular diseases. Recently, a pro-inflammatory subpopulation, known as metabolically activated macrophages (MMe), has been described in conditions of obesity and metabolic syndrome where they are known to release cytokines that can promote insulin resistance. Dyslipidemia represents an important feature in metabolic...
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