Macrophage Polarization in Atherosclerosis.

doi:10.3390/genes13050756

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Article

Macrophage Polarization in Atherosclerosis.

Genes - 25 Apr 2022

Eshghjoo Sahar, Kim Da Mi, Jayaraman Arul, Sun Yuxiang, Alaniz Robert C

Abstract excerpt

The implication of the heterogeneous spectrum of pro- and anti-inflammatory macrophages (Macs) has been an important area of investigation over the last decade. The polarization of Macs alters their functional phenotype in response to their surrounding microenvironment. Macs are the major immune cells implicated in the pathogenesis of atherosclerosis. A hallmark pathology of atherosclerosis is the accumulation of...

Topics

Atherosclerosis
Humans
Macrophage Activation
Macrophages
Phenotype
Plaque, Atherosclerotic

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Open in PubMed Open full text

Identifiers

PMID: 35627141
DOI: 10.3390/genes13050756
PMCID: PMC9142092

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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