Article

Mapping the epitopes of the Human Leukocyte Antigen E antibodies 3D12 and 4D12

2022-05-29

Abstract excerpt

<h4>ABSTRACT</h4> The commonly used commercially available antibodies 3D12 and 4D12 recognise the human leukocyte antigen E (HLA-E) protein. 3D12 is known to exhibit minimal cross-reactivity with classical HLA-Ia allotypes and we confirm that this is also the case for 4D12. These antibodies bind different epitopes on HLA-E, and differ in their ability to recognise alleles of the major histocompatibility complex E...

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Literature Corpus work: ee55f468-29af-530a-bd6b-47f5007e5f56
DOI: 10.1101/2022.05.27.493692

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