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Article

Cell cultures in uterine leiomyomas: rapid disappearance of cells carrying MED12 mutations.

Genes, chromosomes & cancer - 1 Apr 2014

Nadine Markowski Dominique, Tadayyon Mahboobeh, Bartnitzke Sabine, Belge Gazanfer, Maria Helmke Burkhard, Bullerdiek Jörn

Abstract excerpt

Uterine leiomyomas (UL) are the most frequent symptomatic human tumors. Nevertheless, their molecular pathogenesis is not yet fully understood. To learn more about the biology of these common neoplasms and their response to treatment, cell cultures derived from UL are a frequently used model system, but until recently appropriate genetic markers confirming their origin from the tumor cell population were lacking...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24446130
DOI: 10.1002/gcc.22142

Genes

MED12
HMGA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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