Article
A systems-level, semi-quantitative landscape of metabolic flux in C. elegans.
Nature - 1 Apr 2025
Zhang Hefei, Li Xuhang, Tseyang L Tenzin, Giese Gabrielle E, Wang Hui, Yao Bo, Zhang Jingyan, Neve Rachel L, Shank Elizabeth A, Spinelli Jessica B, Yilmaz L Safak, Walhout Albertha J M
Abstract excerpt
Metabolic flux, or the rate of metabolic reactions, is one of the most fundamental metrics describing the status of metabolism in living organisms. However, measuring fluxes across the entire metabolic network remains nearly impossible, especially in multicellular organisms. Computational methods based on flux balance analysis have been used with genome-scale metabolic network models to predict network-level flux...
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