Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic marking of sperm by post-translational modification of histones and protamines

20 Jan 2014

Abstract excerpt

BACKGROUND: The concept that individual traits can be acquired and transmitted by the germline through epigenetic mechanisms has gained recognition in the past years. However, epigenetic marks in sperm have not been are not well identified. RESULTS: Using a novel proteomic approach that combines peptide-based bottom-up and intact protein top-down tandem mass spectrometry, we report the identification of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Genomics and Chromatin Dynamics
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24443974
DOI: 10.1186/1756-8935-7-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic marking of sperm by post-translational modification of histones and protaminesPMID 24443974Read ↗

Comprehensive analysis of histone post-translational modifications in mouse and human male germ cellsSemantic proximity Read ↗

Human sperm chromatin epigenetic potential: genomics, proteomics, and male infertilitySemantic proximity Read ↗

Post‐Translational Modifications of Histones in Human SpermSemantic proximity Read ↗

An aberrant protamine ratio is associated with decreased H4ac levels in murine and human spermSemantic proximity Read ↗

Male mice heterozygous for Protamine-1 and Protamine-2 are infertile displaying sperm damage and retention of Protamine-2 precursors, transition proteins and histonesSemantic proximity Read ↗

Essential Role of Histone Replacement and Modifications in Male FertilitySemantic proximity Read ↗

Histone variants: essential actors in male genome programming.Semantic proximity Read ↗

Chromatin alterations during the epididymal maturation of mouse sperm refine the paternally inherited epigenomeSemantic proximity Read ↗

Sperm histone H3 lysine 4 trimethylation is altered in a genetic mouse model of transgenerational epigenetic inheritance.Semantic proximity Read ↗

The contribution of human sperm proteins to the development and epigenome of the preimplantation embryoSemantic proximity Read ↗

Insights into the sperm chromatin and implications for male infertility from a protein perspectiveSemantic proximity Read ↗

Direct visualization of pre-protamine 2 detects protamine assembly failures and predicts ICSI successSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.