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Article

p53 signaling pathway polymorphisms associated to recurrent pregnancy loss.

Molecular biology reports - 1 Mar 2014

Fraga L R, Dutra C G, Boquett J A, Vianna F S L, Gonçalves R O, Paskulin D D, Costa O L, Ashton-Prolla P, Sanseverino M T V, Schuler-Faccini L

Abstract excerpt

The p53 protein is known for performing essential functions in the maintenance of genomic stability in somatic cells and prevention of tumor formation. Studies of the p53 signaling pathway have suggested associations between some polymorphisms and infertility, post-in vitro fertilization implantation failure and recurrent abortions. The TP53 Pro72Arg polymorphism has been implicated as a risk factor for recurrent...

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Source

Identifiers

PMID: 24435975
DOI: 10.1007/s11033-014-3036-6

Genes

MDM2
LIF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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