Article
Role of p53 codon 72 polymorphism in recurrent pregnancy loss.
Reproductive biomedicine online - 1 Mar 2006
Coulam C B, Kay C, Jeyendran R S
Abstract excerpt
Recurrent pregnancy loss (RPL) has been associated with low expression of apoptosis-and angiogenesis-related genes. The p53 tumour suppressor gene has been shown to induce apoptosis and angiogenesis. Recently, a low increased frequency of a p53 codon 72 polymorphism has been reported among women experiencing RPL. This study investigated the prevalence of p53 codon 72 polymorphism among women with a history of...
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