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A Novel Exon Polymorphism of TP53 Associated with Recurrent Pregnancy Loss in a Chinese Han Population.

Clinical laboratory - 1 Oct 2021

Yu Jin, Zhang Zhendong, Tian Shan, Su Shizhen, Yan Junhao

Abstract excerpt

BACKGROUND: To identify recurrent pregnancy loss (RPL)-related genetic variants in exons of TP53 gene in a population of Chinese Han women. METHODS: This study is a case control study. The cases comprised 90 Chinese Han women with RPL. Another 90 women with at least one child and not more than one miscarriage were recruited as the controls. All exons of TP53 were amplified from genomic DNA and sequenced. RESULTS:...

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PMID: 34655190
DOI: 10.7754/Clin.Lab.2021.201135

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