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Association between TP53 Arg72Pro variant and recurrent pregnancy loss in the Greek population.

Hormone molecular biology and clinical investigation - 1 Dec 2022

Dedousi Dimitra, Mavrogianni Despoina, Papamentzelopoulou Myrto, Stavros Sofoklis, Raouasnte Rami, Loutradis Dimitris, Drakakis Peter

Abstract excerpt

OBJECTIVES: The present case-control study investigates whether TP53 Arg72Pro variant (rs1042522) serves as a risk factor for recurrent pregnancy loss (RPL) in Greek women. METHODS: The study group consisted of 100 patients with at least two miscarriages of unexplained etiology, before the 24th week of gestation. The control group included 106 women with no pregnancy loss history. DNA was extracted and genotyped...

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PMID: 35776848
DOI: 10.1515/hmbci-2021-0093

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