Article
Association of p53 polymorphism with ICSI/IVF failure and recurrent pregnancy loss.
The Australian & New Zealand journal of obstetrics & gynaecology - 1 Apr 2009
Firouzabadi Razieh Dehghani, Ghasemi Nasrin, Rozbahani Maryam Ayazi, Tabibnejad Nasim
Abstract excerpt
BACKGROUND: The p53 tumour suppressor gene is a well-known factor regulating apoptosis in a wide variety of cells. Alterations in the p53 gene are among the most common genetic changes in human cancers. Several polymorphisms of the p53 tumour suppressor gene have been associated with recurrent pregnancy loss (RPL). AIMS: To evaluate the association of polymorphisms p53 codon 72 with the response to in vitro...
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