Article
Association study of frameshift and splice variant polymorphisms with risk of idiopathic recurrent pregnancy loss.
Molecular medicine reports - 1 Aug 2018
Lee Hyun Ah, Ahn Eun Hee, Kim Ji Hyang, Kim Jung Oh, Ryu Chang Soo, Lee Jeong Yong, Cho Sung Hwan, Lee Woo Sik, Kim Nam Keun
Abstract excerpt
Recurrent pregnancy loss (RPL) is defined as ≥2 consecutive pregnancy losses, and can be caused by various factors, including genetics, chromosomal abnormalities, thrombophilia, immune disorders, nutritional factors, environmental factors, psychological stress or maternal infections; however, as many as 50% of RPL cases are idiopathic. In the present study, the role of genetic polymorphisms in RPL was...
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