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Article

Genomic analysis of head and neck squamous cell carcinoma cell lines and human tumors: a rational approach to preclinical model selection.

Molecular cancer research : MCR - 1 Apr 2014

Li Hua, Wawrose John S, Gooding William E, Garraway Levi A, Lui Vivian Wai Yan, Peyser Noah D, Grandis Jennifer R

Abstract excerpt

UNLABELLED: Head and neck squamous cell carcinoma (HNSCC) is the sixth most common type of cancer worldwide. The increasing amount of genomic information on human tumors and cell lines provides more biologic data to design preclinical studies. We and others previously reported whole-exome sequencing data of 106 HNSCC primary tumors. In 2012, high-throughput genomic data and pharmacologic profiling of anticancer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24425785
DOI: 10.1158/1541-7786.MCR-13-0396
PMCID: PMC3989421

Genes

EGFR
CCND2
EGF
ERBB2
FGFR1
NOTCH2
NRAS
PMS1
SMAD4
TRIM33

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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