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Article

Incorporation of Next-Generation Sequencing into Routine Clinical Care to Direct Treatment of Head and Neck Squamous Cell Carcinoma

14 Jan 2016

Abstract excerpt

PURPOSE: The clinical impact of next-generation sequencing (NGS) in patients with head and neck squamous cell carcinoma (HNSCC) has not been described. We aimed to evaluate the clinical impact of NGS in the routine care of patients with HNSCC and to correlate genomic alterations with clinical outcomes. EXPERIMENTAL DESIGN: Single-center study examining targeted NGS platform used to sequence tumor DNA obtained...

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PMID: 26763254
DOI: 10.1158/1078-0432.ccr-15-2314

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