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Article

The molecular landscape of the University of Michigan laryngeal squamous cell carcinoma cell line panel

15 May 2019

Abstract excerpt

BACKGROUND: Laryngeal squamous cell carcinomas (LSCCs) have a high risk of recurrence and poor prognosis. Patient-derived cancer cell lines remain important preclinical models for advancement of new therapeutic strategies, and comprehensive characterization of these models is vital in the precision medicine era. METHODS: We performed exome and transcriptome sequencing as well as copy number analysis of a panel of...

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PMID: 31090975
DOI: 10.1002/hed.25803

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