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Article

Characterization of the CpG island methylator phenotype subclass in papillary thyroid carcinoma.

Frontiers in endocrinology - 1 Jan 2022

Gu Pengfei, Zeng Yu, Ma Weike, Zhang Wei, Liu Yu, Guo Fengli, Ruan Xianhui, Chi Jiadong, Zheng Xiangqian, Gao Ming

Abstract excerpt

CpG island methylator phenotype (CIMP), characterized by the concurrent and widespread hypermethylation of a cluster of CpGs, has been reported to play an important role in carcinogenesis. Limited studies have explored the role of CIMP in papillary thyroid carcinomas (PTCs). Here, in genome-wide DNA methylation analysis of 350 primary PTCs from the Cancer Genome Atlas database that were assessed using the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36353231
DOI: 10.3389/fendo.2022.1008301
PMCID: PMC9637834

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