Article

DNA methylation patterns define subtypes of differentiated follicular cell-derived thyroid neoplasms: an unsupervised machine learning approach

2022-12-19

Abstract excerpt

Alterations in DNA methylation patterns are a frequent finding in cancer. Methylation aberrations can drive tumorigenic pathways and serve as potential biomarkers. The role of epigenetic alterations in thyroid cancer is still poorly understood Here, we analyzed methylome data of a total of 810 thyroid samples (n=256 for discovery and n=554 for validation), including benign and malignant follicular cell-derived thy...

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Literature Corpus work: ec38477f-b810-519d-b459-84dc249bfc04
DOI: 10.1101/2022.12.19.22283657

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