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Article

Comprehensive DNA Methylation Profiling Identifies Novel Diagnostic Biomarkers for Thyroid Cancer.

Thyroid : official journal of the American Thyroid Association - 1 Feb 2020

Park Jong-Lyul, Jeon Sora, Seo Eun-Hye, Bae Dong Hyuck, Jeong Young Mun, Kim Yourha, Bae Ja Seong, Kim Seon-Kyu, Jung Chan Kwon, Kim Yong Sung

Abstract excerpt

Background: There are no reliable biomarkers to accurately differentiate indolent thyroid tumors from more aggressive thyroid cancers. This study aimed to develop new DNA methylation markers for diagnosis and recurrence risk stratification of papillary thyroid carcinoma (PTC). Methods: Thyroid tumor-specific DNA methylation profiling was investigated in 34 fresh frozen tissues, which included nontumor (n = 7),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31797753
DOI: 10.1089/thy.2019.0011

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