Article
Effect of bisphosphonates on the rapidly growing male murine skeleton.
Endocrinology - 1 Apr 2014
Zhu Eric D, Louis Leeann, Brooks Daniel J, Bouxsein Mary L, Demay Marie B
Abstract excerpt
Bisphosphonates are effective for preventing and treating skeletal disorders associated with hyperresorption. Their safety and efficacy has been studied in adults where the growth plate is fused and there is no longitudinal bone growth and little appositional growth. Although bisphosphonate use in the pediatric population was pioneered for compassionate use in the treatment of osteogenesis imperfecta, they are...
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