Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The effects of intravenous pamidronate on the bone tissue of children and adolescents with osteogenesis imperfecta.

The Journal of clinical investigation - 1 Nov 2002

Rauch Frank, Travers Rose, Plotkin Horacio, Glorieux Francis H

Abstract excerpt

Cyclical pamidronate infusions increase bone mass in children suffering from osteogenesis imperfecta. The histological basis for these effects remains unknown. Therefore, we compared parameters of iliac bone histomorphometry from 45 patients before and after 2.4 +/- 0.6 years of pamidronate treatment (age at the time of the first biopsy, 1.4-17.5 years; 23 girls). Although biopsy size did not change significantly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone and Bones
Share to Bone Density

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bone Development

Share to Bone Remodeling

Share to Bone Resorption

Share to Collagen Type I

Share to Diphosphonates

Share to Osteogenesis Imperfecta

Source

Open in PubMed Open full text

Identifiers

PMID: 12417568
DOI: 10.1172/JCI15952
PMCID: PMC151613

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

The effects of intravenous pamidronate on the bone tissue of children and adolescents with osteogenesis imperfecta.PMID 12417568Read ↗

Effect of bisphosphonates on the rapidly growing male murine skeleton.Semantic proximity Read ↗

Intravenous pamidronate treatment in osteogenesis imperfecta.Semantic proximity Read ↗

Intravenous pamidronate in osteogenesis imperfecta type VII.Semantic proximity Read ↗

Pamidronate treatment of osteogenesis imperfecta--lack of correlation between clinical severity, age at onset of treatment, predicted collagen mutation and treatment response.Semantic proximity Read ↗

Cortical bone remodeling in autosomal dominant osteopetrosis: a study of two different phenotypes.Semantic proximity Read ↗

Progressive osseous heteroplasia controlled by intravenous administration of pamidronate.Semantic proximity Read ↗

Intravenous Bisphosphonate Therapy of Young Children With Osteogenesis Imperfecta: Skeletal Findings During Follow Up Throughout the Growing Years.Semantic proximity Read ↗

Bone histomorphometry in adults with type IA osteogenesis imperfecta.Semantic proximity Read ↗

How osteons form: A quantitative hypothesis-testing analysis of cortical pore filling and wall asymmetrySemantic proximity Read ↗

Bone material properties and response to teriparatide in osteoporosis due to WNT1 and PLS3 mutations.Semantic proximity Read ↗

Bone histomorphometry in three females with Rett syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.