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Article

Fracture healing with alendronate treatment in the Brtl/+ mouse model of osteogenesis imperfecta.

Bone - 1 Sept 2013

Meganck J A, Begun D L, McElderry J D, Swick A, Kozloff K M, Goldstein S A, Morris M D, Marini J C, Caird M S

Abstract excerpt

Osteogenesis imperfecta (OI) is a heritable bone dysplasia characterized by increased skeletal fragility. Patients are often treated with bisphosphonates to attempt to reduce fracture risk. However, bisphosphonates reside in the skeleton for many years and long-term administration may impact bone material quality. Acutely, there is concern about risk of non-union of fractures that occur near the time of...

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Identifiers

PMID: 23774443
DOI: 10.1016/j.bone.2013.06.003
PMCID: PMC3999166

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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