Article
Intravenous Bisphosphonate Therapy of Young Children With Osteogenesis Imperfecta: Skeletal Findings During Follow Up Throughout the Growing Years.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Dec 2015
Palomo Telma, Fassier François, Ouellet Jean, Sato Atsuko, Montpetit Kathleen, Glorieux Francis H, Rauch Frank
Abstract excerpt
Cyclical intravenous bisphosphonate therapy is widely used to treat children with osteogenesis imperfecta (OI), but little is known about long-term treatment outcomes. We therefore reviewed 37 children with OI (OI type I, n = 1; OI type III, n = 14; and OI type IV, n = 22) who started intravenous bisphosphonate therapy before 5 years of age (median 2.2 years; range, 0.1 to 4.8 years), and who had a subsequent...
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