Combined effect of five single nucleotide polymorphisms related to IL23/Th17 pathway in the risk of psoriasis.

doi:10.1007/s00251-013-0756-z

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Article

Combined effect of five single nucleotide polymorphisms related to IL23/Th17 pathway in the risk of psoriasis.

Immunogenetics - 1 Mar 2014

Yin Xianyong, Cheng Hui, Zhang Ran, Fan Xing, Zhou Fusheng, Jiang Long, Tang Xianfa, Chen Gang, Zuo Xianbo, Zheng Xiaodong, Yang Sen, Zhang Xuejun

Abstract excerpt

Psoriasis is a common immune-mediated inflammatory skin disease with strong genetic components, in which the IL23/Th17 pathway has been implicated. To explore the effective role in psoriasis, we genotyped five single nucleotide polymorphisms in genes related to IL23/Th17 pathway in 14,929 Han Chinese samples. A Bonferroni-corrected significant single-variant association was identified between rs1512970 within...

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PMID: 24419661
DOI: 10.1007/s00251-013-0756-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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