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Article

Gene-gene interactions in IL23/Th17 pathway contribute to psoriasis susceptibility in Chinese Han population.

Journal of the European Academy of Dermatology and Venereology : JEADV - 1 Sept 2013

Wang W-J, Yin X-Y, Zuo X-B, Cheng H, Du W-D, Zhang F-Y, Yang S, Zhang X-J

Abstract excerpt

BACKGROUND: Psoriasis is a common chronic inflammatory skin disease. IL23/Th17 is a newly confirmed pathway in psoriasis. OBJECTIVE: To investigate the gene-gene interactions in IL23/Th17 pathway underlying psoriasis. METHODS: A total of 299 single-nucleotide polymorphisms from 11 genes in IL23/Th17 pathway were genotyped on 1139 patients with psoriasis and 1694 controls. Multifactor dimensionality reduction and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22909235
DOI: 10.1111/j.1468-3083.2012.04683.x

Genes

CCR4
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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