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Article

Genome-wide association scan yields new insights into the immunopathogenesis of psoriasis.

Genes and immunity - 1 Apr 2009

Elder J T

Abstract excerpt

Psoriasis is a common, immunologically mediated, inflammatory and hyperproliferative disease of the skin and joints, with a multifactorial genetic basis. We earlier mapped PSORS1, the major psoriasis susceptibility gene in the major histocompatibility complex (MHC), to within or very near HLA-Cw6. In an effort to identify non-MHC psoriasis genes, we carried out a collaborative genome-wide association study. After...

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Source

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Identifiers

PMID: 19262574
DOI: 10.1038/gene.2009.11
PMCID: PMC2683580

Genes

APC
TNFAIP3
TNIP1

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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