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Article

Genetic variants in IL-17A rs10484879 and serum levels of IL-17A are associated with psoriasis risk.

Archives of dermatological research - 1 Dec 2022

Akşan Burak, Akadam-Teker Ayşegül Başak

Abstract excerpt

Psoriasis is an inflammatory skin disease characterized by keratinocyte hyperproliferation with effective environmental and genetic factors. Recent studies showing that the IL-23/IL-17 axis plays a central role in the pathogenesis of the disease. Experimental and clinical studies suggest that IL-17A, an important regulatory effector cytokine in this pathway and triggers changes mainly in affected tissues. Based...

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PMID: 34853870
DOI: 10.1007/s00403-021-02308-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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