Article
Association of sixty-one non-synonymous polymorphisms in forty-one hypertension candidate genes with blood pressure variation and hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Aug 2006
Kokubo Yoshihiro, Tomoike Hitonobu, Tanaka Chihiro, Banno Mariko, Okuda Tomohiko, Inamoto Nozomu, Kamide Kei, Kawano Yuhei, Miyata Toshiyuki
Abstract excerpt
We previously selected a group of hypertension candidate genes by a key word search using the OMIM database of NCBI and validated 525 coding single nucleotide polymorphisms (SNPs) in 179 hypertension candidate genes by DNA sequencing in a Japanese population. In the present study, we examined the association between 61 non-synonymous SNPs and blood pressure variations and hypertension. We used DNA samples taken...
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