Article
Association Study of Common Variants in PFN1 With Hypertension in a Han Chinese Population: A Case-Control Study and A Follow-up Study.
American journal of hypertension - 1 Oct 2017
Yang Song, Chen Yanchun, Liu Chunlan, Zhao Xianghai, Zhuang Qian, Sun Junxiang, Wei Pengfei, Zhao Hailong, Chen Xiaotian, Shen Chong
Abstract excerpt
BACKGROUND: Animal researches reported that the dysfunction of profilin1 (PFN1) was involved in the physiological arterial stiffness and vascular remodeling linking to the etiology of hypertension (HT). This study mainly aims at evaluating the association of PFN1 and HT in a Han Chinese population. METHODS: A case-control study consisted of 2,012 HT cases and 2,210 controls was conducted and 2,116 participants...
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