Article
Common variants in the ATP2B1 gene are associated with susceptibility to hypertension: the Japanese Millennium Genome Project.
Hypertension (Dallas, Tex. : 1979) - 1 Nov 2010
Tabara Yasuharu, Kohara Katsuhiko, Kita Yoshikuni, Hirawa Nobuhito, Katsuya Tomohiro, Ohkubo Takayoshi, Hiura Yumiko, Tajima Atsushi, Morisaki Takayuki, Miyata Toshiyuki, Nakayama Tomohiro, Takashima Naoyuki, Nakura Jun, Kawamoto Ryuichi, Takahashi Norio, Hata Akira, Soma Masayoshi, Imai Yutaka, Kokubo Yoshihiro, Okamura Tomonori, Tomoike Hitonobu, Iwai Naoharu, Ogihara Toshio, Inoue Itsuro, Tokunaga Katsushi, Johnson Toby, Caulfield Mark, Munroe Patricia, Umemura Satoshi, Ueshima Hirotsugu, Miki Tetsuro
Abstract excerpt
Hypertension is one of the most common complex genetic disorders. We have described previously 38 single nucleotide polymorphisms (SNPs) with suggestive association with hypertension in Japanese individuals. In this study we extend our previous findings by analyzing a large sample of Japanese individuals (n=14 105) for the most associated SNPs. We also conducted replication analyses in Japanese of susceptibility...
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