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Genetic Ablation of Tau Mitigates Cognitive Impairment Induced by Type 1 Diabetes

7 Jan 2014

Abstract excerpt

Patients affected by diabetes show an increased risk of developing Alzheimer disease (AD). Similarly, patients with AD show impaired insulin function and glucose metabolism. However, the underlying molecular mechanisms connecting these two disorders are still not well understood. Herein, we investigated the microtubule-associated protein tau as a new link between AD and diabetes. To determine whether diabetes...

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PMID: 24412516
DOI: 10.1016/j.ajpath.2013.11.021

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