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Article

Heterozygosity for the hemochromatosis gene in liver diseases--prevalence and effects on liver histology.

Liver - 1 Dec 2000

Höhler T, Leininger S, Köhler H H, Schirmacher P, Galle P R

Abstract excerpt

BACKGROUND/AIMS: The effect of heterozygosity for the C282Y mutation in the HFE hemochromatosis gene on iron accumulation and disease progression in liver disease patients is unclear. METHODS: We investigated the prevalence of this mutation in 531 patients and 205 healthy controls. In addition, we assessed the influence of the mutation on liver histology in 34 C282Y heterozygous and 124 age-, sex- and...

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Source

Identifiers

PMID: 11169063
DOI: 10.1034/j.1600-0676.2000.020006482.x

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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