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Article

The role of vascular endothelial growth factor genetic variability in cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Sept 2009

Schneider Bryan P, Radovich Milan, Miller Kathy D

Abstract excerpt

Angiogenesis is a hallmark of tumor pathogenesis. Vascular endothelial growth factor (VEGF) is a critical regulator of angiogenesis and its inhibition has become a successful approach to antitumor therapy across tumor types. The VEGF gene is highly polymorphic with multiple common single nucleotide polymorphisms (SNPs) in the promoter, 5' untranslated region and 3' untranslated region. There is evidence that...

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Source

Identifiers

PMID: 19706811
DOI: 10.1158/1078-0432.CCR-08-2576

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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