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Article

Nerve growth factor gene polymorphisms may be associated with heroin dependence in women but do not mediate specific personality traits.

European archives of psychiatry and clinical neuroscience - 1 Mar 2025

Kuo Shin-Chang, Lin Chun-Long, Tsou Chang-Chih, Yeh Yi-Wei, Yang Bao-Zhu, Chen Chun-Yen, Huang Chih-Yun, Huang San-Yuan

Abstract excerpt

Heroin dependence (HD) is a complex disease with a substantial genetic contribution and is associated with traits of impulsivity and specific personality traits. The neurotrophic factor nerve growth factor (NGF) may mediate the reward processes in HD. This study aims to investigate whether NGF gene polymorphisms are associated with the co-occurrence of HD and impulsivity/specific personality traits in HD...

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Identifiers

PMID: 39311999
DOI: 10.1007/s00406-024-01906-9
PMCID: PMC11976897

Genes

NGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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