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Article

Integrated analysis of high-resolution DNA methylation profiles, gene expression, germline genotypes and clinical end points in breast cancer patients.

International journal of cancer - 1 Jun 2014

Fleischer Thomas, Edvardsen Hege, Solvang Hiroko K, Daviaud Christian, Naume Bjørn, Børresen-Dale Anne-Lise, Kristensen Vessela N, Tost Jörg

Abstract excerpt

Breast cancer is a heterogeneous disease for which alterations in DNA methylation patterns have been shown to be of biological and clinical importance. Here we report on the integrated analysis of molecular alterations including the methylation status of 27 gene promoters analyzed by highly quantitative pyrosequencing, and the association to gene expression, germline genotype and clinical parameters including...

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Identifiers

PMID: 24395279
DOI: 10.1002/ijc.28606

Genes

OGG1
TFF1
ACVR1
BCAP31

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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