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A seven-gene CpG-island methylation panel predicts breast cancer progression

18 May 2015

Abstract excerpt

BACKGROUND: DNA methylation regulates gene expression, through the inhibition/activation of gene transcription of methylated/unmethylated genes. Hence, DNA methylation profiling can capture pivotal features of gene expression in cancer tissues from patients at the time of diagnosis. In this work, we analyzed a breast cancer case series, to identify DNA methylation determinants of metastatic versus non-metastatic...

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PMID: 25986046
DOI: 10.1186/s12885-015-1412-9

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