Association between PARP-1 V762A polymorphism and breast cancer susceptibility in Saudi population.

doi:10.1371/journal.pone.0085541

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Article

Association between PARP-1 V762A polymorphism and breast cancer susceptibility in Saudi population.

PloS one - 1 Jan 2013

Alanazi Mohammad, Pathan Akbar Ali Khan, Abduljaleel Zainularifeen, Arifeen Zainul, Shaik Jilani P, Alabdulkarim Huda A, Semlali Abdelhabib, Bazzi Mohammad D, Parine Narasimha Reddy

Abstract excerpt

Genetic aberrations of DNA repair enzymes are known to be common events and to be associated with different cancer entities. Aim of the following study was to analyze the genetic association of rs1136410 (Val762Ala) in PARP1 gene with the risk of breast cancer using genotypic assays and insilico structural predictions. Genotypic analysis of individual locus showed statistically significant association of...

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PMID: 24392019
DOI: 10.1371/journal.pone.0085541
PMCID: PMC3877358

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PARP1

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