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Article

BRCA1 mutation spectrum, functions, and therapeutic strategies: The story so far.

Current problems in cancer - 1 Jan 2000

Sharma Babita, Preet Kaur Raman, Raut Sonali, Munshi Anjana

Abstract excerpt

BRCA1 gene mutations account for about 25-28% of hereditary Breast Cancer as BRCA1 is included in the category of high penetrance genes. Except for few commonmutations, there is a heterogenous spectrum of BRCA1 mutations in various ethnic groups. 185AGdel and 5382ins Care the most common BRCA1 alterations (founder mutations) which have been identified in most of the population. This review has been compiled with...

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Source

Identifiers

PMID: 29452958
DOI: 10.1016/j.currproblcancer.2018.01.001

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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