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Article

Association of DNA Repair Gene APE1 Asp148Glu Polymorphism with Breast Cancer Risk.

Disease markers - 1 Jan 2015

AlMutairi Fatima, Pathan Akbar Ali Khan, Alanazi Mohammed, Shalaby Manal, Alabdulkarim Huda A, Alamri Abdullah, Al Naeem Abdulrahman, Elrobh Moammad, Shaik Jilani P, Khan Wajahatullah, Khan Zahid, Parine Narasimha Reddy

Abstract excerpt

OBJECTIVE: The aim of this study was to investigate the role of APE1 Asp148Glu polymorphism in breast cancer progression in Saudi population. METHODS: We examined the genetic variations (rs1130409) in the DNA base excision repair gene APE1 at codon 148 (Asp148Glu) and its association with breast cancer risk using genotypic assays and in silico structural as well as functional predictions. In silico structural...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26257461
DOI: 10.1155/2015/869512
PMCID: PMC4519542

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