Article
Characterization of familial breast cancer in Saudi Arabia.
BMC genomics - 1 Jan 2015
Merdad Adnan, Gari Mamdooh A, Hussein Shireen, Al-Khayat Shadi, Tashkandi Hana, Al-Maghrabi Jaudah, Al-Thubaiti Fatma, Hussein Ibtessam R, Koumosani Taha, Shaer Nehad, Chaudhary Adeel G, Abuzenadah Adel M, Al-Qahtani Mohammed H, Dallol Ashraf
Abstract excerpt
BACKGROUND: The contribution of genetic factors to the development of breast cancer in the admixed and consanguineous population of the western region of Saudi Arabia is thought to be significant as the disease is early onset. The current protocols of continuous clinical follow-up of relatives of such patients are costly and cause a burden on the usually over-stretched medical resources. Discovering the...
Topics
- BRCA1 Protein
- BRCA2 Protein
- Breast Neoplasms
- DNA Helicases
- DNA Repair Enzymes
- Exome
- Female
- Genetic Predisposition to Disease
- High-Throughput Screening Assays
- Humans