Article
T Cells Modulate Epstein-Barr Virus Latency Phenotypes during Infection of Humanized Mice
3 Jan 2014
Abstract excerpt
UNLABELLED: Human B cells, the main target of Epstein-Barr virus (EBV), can display several types of latent viral protein expression, denoted 0, I, IIa, IIb, or III. Of these, only type III expression induces proliferation of cells in vitro. These latency types are present at specific stages of infection and are also characteristic of different tumor types, but their generation is not fully understood. In this...
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