Epstein–Barr virus activates β-catenin in type III latently infected B lymphocyte lines: Association with deubiquitinating enzymes

Abstract excerpt

beta-Catenin is a multifunctional protein, stabilization of which is a critical step in its functional activity. Stabilization can be conferred through several means, including mutations in beta-catenin, common in many carcinomas. In this article, we explore the effect of viral infection on the beta-catenin signaling pathway in B lymphocytes, including cell lines derived from lymphomas. Infection by the human...

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