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Article

EBNA3B-deficient EBV promotes B cell lymphomagenesis in humanized mice and is found in human tumors.

The Journal of clinical investigation - 1 Apr 2012

White Robert E, Rämer Patrick C, Naresh Kikkeri N, Meixlsperger Sonja, Pinaud Laurie, Rooney Cliona, Savoldo Barbara, Coutinho Rita, Bödör Csaba, Gribben John, Ibrahim Hazem A, Bower Mark, Nourse Jamie P, Gandhi Maher K, Middeldorp Jaap, Cader Fathima Z, Murray Paul, Münz Christian, Allday Martin J

Abstract excerpt

Epstein-Barr virus (EBV) persistently infects more than 90% of the human population and is etiologically linked to several B cell malignancies, including Burkitt lymphoma (BL), Hodgkin lymphoma (HL), and diffuse large B cell lymphoma (DLBCL). Despite its growth transforming properties, most immun...

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Share to Cell Transformation, Viral
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epstein-Barr Virus Infections

Share to Epstein-Barr Virus Nuclear Antigens

Share to Lymphoma, B-Cell

Share to Lymphoproliferative Disorders

Share to Postoperative Complications

Share to Tumor Virus Infections

Source

Open in PubMed Open full text

Identifiers

PMID: 22406538
DOI: 10.1172/JCI58092
PMCID: PMC3314448

Genes

CXCL10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22406538-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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