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Article

Lymphoma induction by human B cells in scid mice.

Leukemia - 1 Jan 1992

Amadori A, Veronese M L, Mazza M R, Zamarchi R, Mion M, D'Andrea E, Menin C, Del Mistro A, Leszl A, Calderazzo F

Abstract excerpt

Lymphoma development was studied in scid mice injected i.p. with PBMC from EBV-positive donors. Most injected mice developed oligo/monoclonal B-cell tumors within 4 months after the inoculation; EBV genome was found in tumor cells. Removal of T lymphocytes from the injected cell populations prevented lymphoma development in all mice, suggesting that T-cell-derived factors are involved in the expansion of the...

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PMID: 1318472

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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