Reduced ADAMTS13 activity is associated with an ADAMTS13 SNP, fever and microparticles in a malaria-like model.

doi:10.1186/1475-2875-13-3

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Article

Reduced ADAMTS13 activity is associated with an ADAMTS13 SNP, fever and microparticles in a malaria-like model.

Malaria journal - 3 Jan 2014

Kraisin Sirima, Palasuwan Attakorn, Popruk Supaluk, Nantakomol Duangdao

Abstract excerpt

BACKGROUND: Severe falciparum malaria (SM) remains a major cause of death in tropical countries. The reduced activity of ADAMTS13, increasing levels of ultra-large von Willebrand factor (ULVWF) in SM patients, are assumed as factors that intensify disease severity. However, the reason why ADAMTS13 activity is reduced in SM remains unclear. OBJECTIVES: To investigate whether rs4962153, febrile temperature, and...

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PMID: 24386898
DOI: 10.1186/1475-2875-13-3
PMCID: PMC3882324

Genes

ADAMTS13

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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