Article
The association between TNFα gene polymorphisms and susceptibility to rheumatoid arthritis in an ethnic Kashmiri population: relationship with disease activity and severity markers.
International journal of rheumatic diseases - 1 Apr 2016
Shafia Syed, Sofi Fayaz A, Dilafroze, Rasool Roohi, Javeed Sheikh, Shah Zafar A
Abstract excerpt
AIM: The aim of our study was to determine the genetic associations between polymorphisms of the TNFα gene (-308G/A and -238G/A) with disease susceptibility and severity in patients with rheumatoid arthritis (RA) in an ethnic Kashmiri population. METHODS: Allele and genotype frequencies of TNFα-308G/A and TNFα-238G/A polymorphisms were compared between 150 RA patients and 200 healthy controls by using polymerase...
Topics
- Adult
- Arthritis, Rheumatoid
- Case-Control Studies
- Female
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- Health Status Indicators
- Humans
- India