Article
The association between TNFα gene polymorphisms and susceptibility to rheumatoid arthritis in an ethnic Kashmiri population: relationship with disease activity and severity markers.
International journal of rheumatic diseases - 1 Apr 2016
Shafia Syed, Sofi Fayaz A, Dilafroze, Rasool Roohi, Javeed Sheikh, Shah Zafar A
Abstract excerpt
AIM: The aim of our study was to determine the genetic associations between polymorphisms of the TNFα gene (-308G/A and -238G/A) with disease susceptibility and severity in patients with rheumatoid arthritis (RA) in an ethnic Kashmiri population. METHODS: Allele and genotype frequencies of TNFα-308G/A and TNFα-238G/A polymorphisms were compared between 150 RA patients and 200 healthy controls by using polymerase...
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