Article
TNF-α-308 polymorphism determines clinical manifestations and therapeutic response of ankylosing spondylitis in Han Chinese.
Medicina clinica - 20 Dec 2017
Ma Hai-Jun, Yin Qing-Feng, Wu Yin, Guo Ming-Hao
Abstract excerpt
BACKGROUND AND OBJECTIVE: There is ongoing debate as to whether tumor necrosis factor alpha (TNF-α)-308 is associated with ankylosing spondylitis (AS). The aim of the present study was to determine whether TNF-α-308 is involved into genetic susceptibility, clinical features and therapeutic response of AS in Han Chinese. METHODS: Two hundred and sixty AS patients with 260 ethnically matched healthy blood donors...
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