Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial DNA alterations and mitochondrial dysfunction in the progression of hepatocellular carcinoma.

World journal of gastroenterology - 21 Dec 2013

Hsu Chia-Chi, Lee Hsin-Chen, Wei Yau-Huei

Abstract excerpt

Hepatocellular carcinoma (HCC) is one of the most common malignancies and is ranked third in mortality among cancer-related diseases. Mitochondria are intracellular organelles that are responsible for energy metabolism and cellular homeostasis, and mitochondrial dysfunction has been regarded as a hallmark of cancer. Over the past decades, several types of mitochondrial DNA (mtDNA) alterations have been identified...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to Disease Progression

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to DNA, Mitochondrial

Share to Genetic Predisposition to Disease

Share to Liver Neoplasms

Share to Mitochondria, Liver

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 24379611
DOI: 10.3748/wjg.v19.i47.8880
PMCID: PMC3870539

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial DNA alterations and mitochondrial dysfunction in the progression of hepatocellular carcinoma.PMID 24379611Read ↗

Somatic mitochondrial DNA mutations in human cancers.Semantic proximity Read ↗

Somatic mutations of mitochondrial DNA in aging and cancer progression.Semantic proximity Read ↗

Functional Role of Mitochondrial DNA in Cancer Progression.Semantic proximity Read ↗

Generation, function and diagnostic value of mitochondrial DNA copy number alterations in human cancers.Semantic proximity Read ↗

Mitochondrial defects in cancer.Semantic proximity Read ↗

Mitochondria act as a key regulatory factor in cancer progression: Current concepts on mutations, mitochondrial dynamics, and therapeutic approach.Semantic proximity Read ↗

The Significance of Mitochondrial Dysfunction in Cancer.Semantic proximity Read ↗

Deciphering the Spectrum of Mitochondrial DNA Mutations in Hepatocellular Carcinoma Using High-Throughput Sequencing.Semantic proximity Read ↗

Deregulated Mitochondrial DNA in Diseases.Semantic proximity Read ↗

Mitochondrial dynamics, quality control, and mtDNA in alcohol-associated liver disease and liver cancerSemantic proximity Read ↗

Molecular alterations in mitochondrial DNA of hepatocellular carcinomas: is there a correlation with clinicopathological profile?Semantic proximity Read ↗

Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.